Novel Aspects of Pain Management

Novel Aspects of Pain Management

Opioids and Beyond

eBook - 1999
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Neuronal Nicotinic Receptors
Pharmacology and Therapeutic Opportunities
Edited by Stephen P. Arneric and Jorge D. Brioni
Providing a comprehensive review of nicotinic receptors, this reference examines all aspects-from the molecular level to clinical applications. The editors cover the emerging molecular biological advances in the cloning of nAChRs, as well as the localization and regulation of these receptors, and the role these receptors have in central nervous system (CNS) disorder functions. Additionally, examined areas include in vivo pharmacology, and the therapeutic opportunities existing for agents that selectively interact with these receptors to treat CNS disorders.
1999 (0-471-24743-X) 440 pp.

Purinergic Approaches in Experimental Therapeutics
Edited by Kenneth A. Jacobson and Michael F. Jarvis
Purinergic receptors are a type of neuroreceptor that has been found to have unique therapeutic potential as a chemical compound in the treatment of many neurological disorders such as Alzheimer's disease, chronic pain, Parkinson's disease, stroke, thrombosis, bladder function, stress, and cancer. This book covers the molecular pharmacology, medicinal chemistry, and experimental therapeutics of purinergic compounds.
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Book News
Scientists and scholars from Canada, the US, Britain, and France review the new classes of drugs being developed to manage, reduce, and relieve pain. They consider properties of the many chemicals that influence pain processing, provide historical perspectives on the classes of agents, and assess their potential for therapeutic development. Among the topics are animal models of pain, recent advances in the pharmacology of opioids, vanilloids as analgesics, neurokinin antagonists, serotonin and its receptors in pain control, the potential of purines as analgesic agents, tricyclic and other antidepressants, voltage-gated ion channel modulators, and spinal drug interactions. Annotation c. Book News, Inc., Portland, OR (

Publisher: New York, N.Y. : Wiley-Liss, c1999
ISBN: 9780585273396
Characteristics: 1 online resource (xi, 373 p.) : ill
Additional Contributors: Cowan, Alan 1942-
Sawynok, Jana 1950-


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